Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
نویسندگان
چکیده
منابع مشابه
Distribution of fasting plasma insulin, free fatty acids, and glucose concentrations and of homeostasis model assessment of insulin resistance in a representative sample of Quebec children and adolescents.
BACKGROUND Plasma fasting insulin and the homeostasis model assessment of insulin resistance (HOMA-IR) are markers of IR, which, at least in part, mediates the relation of obesity to increased cardiovascular risk. Increased free fatty acids (FFAs) may be involved in the pathogenesis of IR. Our objectives were to describe the distributions of fasting plasma insulin, glucose, and FFAs and HOMA-IR...
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BACKGROUND & OBJECTIVES Lowering the diagnostic threshold of normal fasting plasma glucose (FPG) from 6.1 to 5.56 mmol/l has been proposed by American Diabetes Association. As early detection of subjects with risk of diabetes is important, it is crucial to understand the relationship between different levels of FPG, insulin resistance (IR) and insulin secretion. We measured IR and insulin secre...
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OBJECTIVE Simple fasting methods to measure insulin resistance, such as the homeostasis model assessment (HOMA), fasting glucose/insulin ratio (FGIR), and quantitative insulin sensitivity check index (QUICKI) methods, have been widely promoted for adult studies but have not been evaluated formally among children and adolescents. The aim of this study was to compare the HOMA, FGIR, and QUICKI me...
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Type 2 diabetes mellitus consists of metabolic disturbances characterised mainly characterized by hyperglycemia which usually result from the combination of resistance to insulin action, inadequate insulin secretion, and excessive or inappropriate glucagon secretion. In clinical practice its very difficult to establish how much part of this metabolic disturbances is due to lack of insulin and h...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1985
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf00280883